19 Greet Prisca and Aquila, and the household of Onesiphorus.
20 Erastus stayed in Corinth, but Trophimus I have left in Miletus sick.
21 Do your utmost to come before winter. Eubulus greets you, as well as Pudens, Linus, Claudia, and all the brethren.
22 The Lord Jesus Christ be with your spirit. Grace be with you. Amen.
Prisca and Aquila (v.19) — Paul’s long-standing helpers and friends (Acts 18:2; Acts 18:18; Acts 18:26; Romans 16:3; 1 Corinthians 16:19). Priscilla (the name by which she is usually called in Scripture) is a diminutive of Prisca
Onesiphorus (v.19) — 2 Timothy 1:16-18
Trophimus (v.20) — the innocent cause of Paul’s arrest in Jerusalem (Acts 21:29)
Verse 20 also emphasizes the fact that the sign gifts had indeed vanished. He had had to leave Trophimus at Miletum sick. If the gift of healing had still been in order what could possibly have been the reason for Paul’s writing to Timothy that he had left Trophimus, a faithful companion, sick along the way to Rome? — Stam, page 228
you (v.22) — plural — Timothy and those with him in Ephesus